Which anti-COVID-19 drugs could work?

    The whole world is frightened and nervous due to the spread of baneful Coronavirus. COVID 19 cases and deaths are increasing every day. As of 17th April, this communicable disease has taken over 146,856 lives. Government and health experts have recommended to stay at home to prevent the spread of this epidemic, as this virus spreads from person to person.

    The lethal spread of this virus has lead to worldwide lockdown and has brought down the economies. Scientists and policymakers are looking to provide safe and successful therapies for the ill to get rid of this crucial situation. But COVID-19 is still a big problem of which no cure exists to date.

    Although research conducted for Coronavirus has produced some promising drugs over the last few decades, the safety and efficacy of these treatments can only be determined by major clinical trials of COVID-19 patients. Unfortunately, these major trials take time to complete, but they are still in the process.

    The World Health Organization has announced that it will initiate four ‘major trials’ against COVID-19, which will be organized by several smaller countries across the globe.
    Besides this, it is also reported that the WHO-funded trials concentrate on medicines which are expected to stop the virus strain SARS-CoV-2 from replicating within our pulmonary system, which causes COVID-19.

    Remdesiviris is an intravenous antiviral medication that has been developed to stop coronavirus infection, restricting it to spread like ebola. According to reports, Remdesivir was already used in some COVID-19 patients in the United States and seemed secure; however, major studies are needed to find out if this is valid.

    Apparently, Chloroquine and hydroxychloroquine are used in the treatment of malaria and autoimmune lupus disease. A number of pathogens have been studied in the laboratory, Chloroquine is able to avoid viruses-like SARS-CoV-2-from penetrating the dish inside cells and avoiding infection. Chloroquine has not shown to have a profound effect on disease prevention outside the laboratory, and there is little evidence that it may function for COVID-19. However, President Donald Trump has given it a lot of attention.

    A drug combination of Lopinavir/Ritonavir, which was used against viruses like HIV, is found effective against SARS-COV-2 in lab cells as well as in mice. The test of this drug is being conducted for an antiviral drug called interferon beta.

    Restricted research on COVID-19 indicates that our immune response overflows in certain severe cases without the opportunity to eradicate the infection, which may increase the seriousness of the disease. High inflammation in the lungs occurs when this takes place.
    Being precise, COVID-19 drugs are not yet available, medications have been tested, and clinical trials have started and yielded results. In tandem with more information about SARS-CoV-2 scientists, this will help immensely before a vaccine is available.

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